https://nuheals.com/oxycodone-vs-fentanyl/ Oxycodone and fentanyl are two powerful opioids commonly prescribed for managing severe pain, but they differ significantly in their potency, onset of action, and potential side effects. Oxycodone is often used for moderate to severe pain relief and is available in both immediate-release and extended-release formulations, making it versatile for various pain management needs. It works by binding to opioid receptors in the brain, effectively altering the perception of pain and providing a sense of relief. Patients may find oxycodone to be a suitable option for chronic pain conditions, post-surgical recovery, or injury-related discomfort, as it allows for a controlled and gradual approach to pain management.