https://nuheals.com/how-long-does-oxycodone-stay-in-your-system/ Oxycodone is a powerful prescription opioid used to manage moderate to severe pain, but understanding how long it remains detectable in your system is crucial for various reasons, including medical testing and personal health management. Typically, oxycodone can be detected in urine for up to 3-4 days after the last dose, while blood tests may reveal its presence for 24 hours, and hair follicle tests can show traces for up to 90 days. Factors such as dosage, frequency of use, metabolism, and individual health conditions can significantly influence these detection windows. Knowing this information is essential for patients and healthcare providers alike, ensuring safe and responsible use of this medication while minimizing the risk of dependency and potential side effects.