https://nuheals.com/can-oxycodone-cause-insomnia/ Oxycodone, a powerful opioid analgesic, is primarily prescribed for the management of moderate to severe pain. However, one of the lesser-known side effects associated with its use is the potential for sleep disturbances, including insomnia. This can be particularly concerning for patients who rely on the medication for pain relief while also needing restorative sleep. The mechanism behind this side effect may involve the drug's impact on the central nervous system, which can alter sleep architecture and lead to difficulties in both falling asleep and maintaining sleep throughout the night. Understanding this relationship is crucial for patients and healthcare providers alike, as it can influence treatment plans and overall quality of life.