Technology

Cardiac safety evaluation is an important factor that must be investigated before various new drugs enter clinical trials, and it is also one of the most important and difficult links in the early clinical research of innovative drugs. The QT interval of the heart refers to the period from the beginning of the QRS complex to the end of the T wave, including the process of ventricular depolarization and repolarization. The QT interval is considered to be one of the key indicators for the safety evaluation of new drugs. In cardiomyocytes, the potassium channel encoded by hERG (human Ether-a-go-go Related Gene) mediates a delayed rectifier potassium current (IKr), and IKr inhibition is an important mechanism by which drugs lead to prolongation of the QT interval. hERG can be inhibited by compounds with diversified structures. The loss of its function or drug inhibition will affect the repolarization process of cardiac action potentials and cause the QT interval to prolong. At the same tim

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ChatGPT is an advanced conversational AI developed by OpenAI, powered by the GPT-3.5 architecture. It is designed to engage in natural language conversations with users and provide accurate,

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In the formulation of GLP-1 integrated research plan, Medicilon has in-depth communication with customers. Medicilon provides GLP-1 drug discovery, CMC research (API + formulation), pharmacodynamics research, PK study, GLP-1 safety evaluation and other services.https://www.medicilon.com/platform/drug-discovery/

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Shanghai Medicilon Inc. (Medicilon) has the honor to interview Dr. Fei Zhang, the founder of Raymon Pharma, to share his unique insights in the field of ophthalmic drugs.

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Artificial Intelligence (AI) has emerged as a game-changing technology, revolutionizing industries and transforming the way we live and work. As AI continues to advance, it is essential to explore its impact and the remarkable possibilities it brings. In this article, we delve into the advent of AI technology, highlighting its evolution from algorithms to intelligence and its profound implications for society. Join us as we navigate the exciting landscape of AI and its growing significance in various domains.

Recently, the IND application of TollB-001 Tablets, a class 1.1 new drug for rheumatoid arthritis by Toll Biotech, has been officially approved by the FDA. Medicilon provided pharmaceutical research services, including raw materials and preparation, for TollB-001 tablets, which accelerated the research process.

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Metamask Wallet is a browser extension for Google Chrome that allows users to manage their Ethereum-based assets and interact with dApps seamlessly

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