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Genotoxic impurities are compounds that directly or indirectly damage cellular DNA, produce genetic mutations or mutagenesis in vivo, and have carcinogenic potential or propensity. It is characterized by damage to human genetic material at very low concentrations, leading to genetic mutations and possibly tumorigenesis. Genotoxic impurities commonly found in the pharmaceutical industry include: Sulfonates Alkyl Halides and Esters Hydrazines Epoxides Aromatic Compounds β-lactam Related Impurities Genotoxic Impurities Analysis Fig. 1. Structures of common sulfonate salts1 Because genotoxic impurities are highly toxic and threaten the public's medication safety, they need to be risk assessed and controlled. Alfa Chemistry is an expert in the analytical chemistry industry, providing solutions for the development and analysis of chemical methods for the detection of trace amounts of genetic impurities for the complex pharmaceutical industry. We design custom-complia

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Tyrese Maxey scored 30 points despite a bloody nose from Brandon Miller's flagrant foul, Kelly Oubre Jr. added 22, and the Philadelphia 76ers held off a fourth-quarter charge to defeat the Charlotte Hornets 109-98 on Saturday night. "I'm all right," Maxey said after the second-quarter collision.

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What are the Organic Field Effect Transistors (OFETs)? Organic Field Effect Transistors (OFETs) have gained significant attention in recent years due to their unique properties and potential applications in the field of organic electronics. As the demand for flexible and stretchable electronics continues to grow, the development of OFET materials that can withstand mechanical stress and strain becomes crucial. What are the Advancements in Flexible and Stretchable OFET Materials? 1. Elastomeric Substrates: One of the key requirements for achieving flexibility and stretchability in OFETs is the use of elastomeric substrates. These substrates, typically made of polymers such as polydimethylsiloxane (PDMS), offer excellent mechanical properties and can be easily deformed without compromising the performance of the transistor. By integrating OFETs with elastomeric substrates, researchers have been able to achieve high levels of flexibility, opening up possibilities for wearable elec

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